I've been online on news sites and forums all day long as well as bouncing back and forth between CNN and Fox News for the few pitiful updates they've running about the Mexican Swine Flu outbreak. Before you read any further, please be advised that some of what I'm about to write will be speculative on my part, so you should absorb it and then make your own decision as to whether or not the ideas I present hold water. Also, I'm going to be reporting a few things that I don't have links to back-up because I listened-in on a media Q&A conference call with WHO and CDC officials earlier today and took notes.
Now, with that said, allow me to quickly rehash why I find this particular new flu strain troublesome as stated in
yesterday's article. My reasoning, as I explained previously, is thus:
- This is an entirely new H1N1-series variant influenza that the human immune system has never before gone up against, and therefore we have no natural antibodies with which to attack it. This was also true of the 1918-1920 Spanish flu pandemic.
- It has manifested a wide geographical spread, appearing unexpectedly in far-flung places within a short period of time. Again, this was also the case during the 1918-1920 Spanish flu pandemic.
- Most of the fatalities have been in adult subjects under the age of 45, which is the group usually most resistant to these types of illnesses. This, once again, mirrors the 1918-1920 Spanish flu pandemic which killed large numbers of seemingly healthy subjects by enducing cytokine storms.
It is now possible to draw a fourth comparison to the 1918-1920 pandemic as it has been confirmed that the virus is recombinant, containing pig, bird, and human genetic material, and is now freely communicable among the human population. Basically, the very thing scientists have feared
might one day happen with H5N1 Avian or "bird" flu
has now happened (past tense) with H1N1 Swine flu. The only thing that remains to be seen is how far it spreads and how deadly it will be.
When I wrote last night's article (roughly 24 hours ago), there were 68 confirmed deaths in Mexico; the official number is now 81. If you're the tinfoil hat conspiracy type, there are reports online from people who are supposedly in Mexico that claim the number is more like 200+, and the reports being given to the mainstream media are purposefully being low-balled to avoid panic. At least one such claim was picked-up and carried by the BBC earlier today, so who knows if it's accurate or not. Further, last night there were a handful of U.S. cases reported in both Texas and California; now, those cases are confirmed as are two in Kansas and a whole slew in New York. I'm also seeing internet chatter about Chile, Michigan, Minnesota, and Montreal, and about someone on a British Airways flight being isolated after falling ill while in transit, but none of those are yet confirmed. So, I think I'm safe in saying that however severe this turns out to be, it is definitely still going strong and spreading.
Now, before I go any further, you may be thinking that 81 people doesn't sound like a terribly high mortality rate, but keep in mind these are only those that have been confirmed via tissue samples (a somewhat slow, backed-up process) and we were assured that, sadly, the number would most likely continue to rise as there are many more waiting to be tested.
Another question that came up during the Q&A was why does it seem to be so much more deadly in Mexico, as none of the U.S. cases have yet resulted in fatalities?
The CDC representative said that they aren't sure about this, but that
they fully expect we will see deaths in the U.S., it just hasn't happened yet. It was a bit of a shock because he said it rather matter-of-factly and the call actually went quiet for a few seconds after that; it was very surreal.
Now, here is where I'm going to get into some speculation as a few things have been rattling around my head all day, and I feel the need to flesh them out a bit. While researching the 1918-1920 Spanish flu pandemic today, I realized that one of the characteristics of pandemic influenza is that it comes in waves; the first cases were reported in the Spring of 1918 and were comparably mild. But then, the virus mutated and returned in the Fall with guns-a-blazin', and rampaged around the globe before finally subsiding in the Summer of 1920. It was with that in mind that I came across a post on an internet forum I frequent where the author posed the question: what if the Mexican and U.S. strains are different waves? Now, I'm not sure what to say to that nor am I qualified really. With regard to the seemingly higher levels of mortality in Mexico, though, I have to say it's intriguing. Anyway, that led me to do some further research and I came across some evidence that might back-up the idea that this thing didn't just come out of left field, but has instead been simmering for a few weeks.
First, there's
this timeline that points to a man who returned from a trip to Mexico on March 22 sporting an unknown illness, for which he was hospitalized 8 days later. Then, on April 6,
"... local health officials declared a health alert due to a respiratory disease outbreak in La Gloria, Perote Municipality, Veracruz State, Mexico. Sources characterized the event as a "strange" outbreak of acute respiratory infection, which led to bronchial pneumonia in some pediatric cases. According to a local resident, symptoms included fever, severe cough, and large amounts of phlegm. Health officials recorded 400 cases that sought medical treatment in the last week in La Gloria, which has a population of 3,000; officials indicated that 60% of the town’s population (approximately 1,800 cases) has been affected. No precise timeframe was provided, but sources reported that a local official had been seeking health assistance for the town since February. Residents claimed that three pediatric cases, all under two years of age, died from the outbreak. However, health officials stated that there was no direct link between the pediatric deaths and the outbreak; they stated the three fatal cases were "isolated" and "not related" to each other.
Residents believed the outbreak had been caused by contamination from pig breeding farms located in the area."Read the document for yourself as there is more that I didn't quote. To my mind, this begs the question of whether these occurrences might be linked in some way.
Along the same lines, one should note that mid-March is a popular time for thousands of wild college kids to descend on Mexico for Spring Break, so if this thing was floating around down there at that time then it would have been spread all over the U.S.. And, oddly enough, a few weeks ago there was a rather nasty respiratory infection that made it's rounds through many parts of the country. Reports abound on the internet of individuals claiming to have just recently gotten over a nearly debilitating illness that they just assumed was a particularly bad "summer cold." Could it be that these folks were actually suffering from an early wave of the Mexican Swine Flu?
What if the flu started out milder in Mexico as well, and what we are seeing down there now is when it picks up steam? Is it really difficult to imagine earlier, milder cases going unnoticed and under-reported? The earliest mentions of sickness in Mexico seem to go back to sometime in February, which would point to approximately 2 months between the first and current "more deadly" waves.
With that in mind, could we be in for an interesting month of June, or might it ramp up sooner? Or never? Your guess is as good as mine.